🧵 Thread: Enzyme (CYT P-450) Inducers & Inhibitors for USMLE! 📚💊
1️⃣
Understanding enzyme inducers and inhibitors is crucial for the USMLE! Let's break it down with easy mnemonics. 🧠💡
1️⃣
Understanding enzyme inducers and inhibitors is crucial for the USMLE! Let's break it down with easy mnemonics. 🧠💡
2️⃣
Enzyme Inducers:
Remember "CRAP GPS" 🚗🛰️
🔺C: Carbamazepine
🔺R: Rifampin
🔺A: Alcohol (chronic)
🔺P: Phenytoin
🔺G: Griseofulvin
🔺P: Phenobarbital
🔺S: Sulfonylureas
Enzyme Inducers:
Remember "CRAP GPS" 🚗🛰️
🔺C: Carbamazepine
🔺R: Rifampin
🔺A: Alcohol (chronic)
🔺P: Phenytoin
🔺G: Griseofulvin
🔺P: Phenobarbital
🔺S: Sulfonylureas
3️⃣
Mnemonic in Action:
"Car Rides Accelerate People Going Places Swiftly." 🚗💨
Mnemonic in Action:
"Car Rides Accelerate People Going Places Swiftly." 🚗💨
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Effects:
Inducers lower levels of drugs like warfarin, OCPs, and theophylline by speeding up metabolism.
Effects:
Inducers lower levels of drugs like warfarin, OCPs, and theophylline by speeding up metabolism.
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Enzyme Inhibitors:
"SICKFACES.COM Group"
S: Sodium valproate
I: Isoniazid
C: Cimetidine
K: Ketoconazole
F: Fluconazole
A: Alcohol (acute)
C: Chloramphenicol
E: Erythromycin
S: Sulfonamides
C: Ciprofloxacin
O: Omeprazole
M: Metronidazole
G: Grapefruit juice
Enzyme Inhibitors:
"SICKFACES.COM Group"
S: Sodium valproate
I: Isoniazid
C: Cimetidine
K: Ketoconazole
F: Fluconazole
A: Alcohol (acute)
C: Chloramphenicol
E: Erythromycin
S: Sulfonamides
C: Ciprofloxacin
O: Omeprazole
M: Metronidazole
G: Grapefruit juice
7️⃣
Effects:
Inhibitors increase drug levels, raising the risk of toxicity for drugs like warfarin, statins, and antiepileptics.
Effects:
Inhibitors increase drug levels, raising the risk of toxicity for drugs like warfarin, statins, and antiepileptics.
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Quick Recap:
🔺Inducers (CRAP GPS): Decrease drug levels
🔺Inhibitors (SICKFACES.COM Group): Increase drug levels
Quick Recap:
🔺Inducers (CRAP GPS): Decrease drug levels
🔺Inhibitors (SICKFACES.COM Group): Increase drug levels
9️⃣
Pro Tip:
Chronic alcohol use induces enzymes, while acute use inhibits them. 🥂📉
Pro Tip:
Chronic alcohol use induces enzymes, while acute use inhibits them. 🥂📉
🔟
Memorize these mnemonics to ace your USMLE! Good luck, future doctors! 🍀👩⚕️👨⚕️
#USMLE #MedTwitter #Pharmacology #MedStudent
Memorize these mnemonics to ace your USMLE! Good luck, future doctors! 🍀👩⚕️👨⚕️
#USMLE #MedTwitter #Pharmacology #MedStudent
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