Nick Norwitz
Nick Norwitz

@nicknorwitz

2 تغريدة Mar 11, 2024
Microplastics in Arteries Associated with ~350% higher prevalence of Heart Attack, Stroke and Death ☠️
In this video (youtu.be), I cover the new @NEJM data, and provide 11 tips to reduce Microplastics exposure
👉 n = 257 people followed for ~34 months
👉 4.53 Hazards ratio of Heart Attack, Stroke and Death if microplastics and nanoplastic particles (MNPs) were in their carotid arteries
👉 Those with MNP and no MNPs detected were similar along other risk parameters
11 tips
👉 Don't eat packaged food (duh!)
👉 Don't heat plastic (double duh!)
👉 Avoid those plastic baggies at groceries stories for buying produce, if possible
👉 Avoid cans, or look for BPA-free cans
👉 Natural fabric clothing (wool, cotton) > Polyester
👉 Same for carpets... and vacuum!
👉 Avoid synthetic sponges and brushes. You can buy those made of plant cellulose or coconut fiber, etc. instead
👉 Avoid heavy traffic roads (keep windows up during heavy traffic)
👉 ❌🦐🦪🦞 (NOOO!!!!! UGHHH!!!!)
👉 There are self-care products, e.g. toothpastes, deodorants etc. that are low or no microplastics
👉 OF COURSE... don't use plastic water bottles. Bad for you and bad for 🐢 'Mr. Dude' (if you get the Nemo reference)
Check out video: youtu.be
paper: nejm.org
nb: *A criticism of the data in this paper will be that they are "associative." This was an "observational" trial, not an RCT. Technically, causality isn't proven. However, it's important to keep in mind that (1) You can't do an RCT on this topic with hard outcomes... you can't randomize a group a humans to microplastics exposure and then monitor for the outcomes of heart attack, stroke and death. (2) These data are consistent with prior work and have biological plausibility, i.e. there are data that microplastics can induce an inflammatory and immune response, signs of which we also see in this paper with the increase in immune cell activation markers and inflammatory cytokines (3) In general, the "cost" to reducing microplastics is inconvenience at most. If you choose to drink filtered tap water out of your own stainless steel bottle, rather than bottled, at absolute worst you get negligible health benefit and that water bottle doesn't end up in the ocean as pollution.
"In this randomized clinical trial of 285 firefighters, both blood and plasma donations resulted in significantly lower PFAS levels than observation alone.
Plasma donation was the most effective intervention, reducing mean serum perfluorooctane sulfonate levels by 2.9 ng/mL compared with a 1.1-ng/mL reduction with blood donation, a significant difference; similar changes were seen with other PFASs."
*perfluoroalkyl and polyfluoroalkyl substances (PFASs)
jamanetwork.com

جاري تحميل الاقتراحات...