— Don’t give —
— لا تُعطي —
هي سلسلة من التغريدات متجددة لأهم التعارضات الدوائية مهمة لصيادلة وللأطباء وأيضًا لكل مهتم بالتثقيف الصحي.
— لا تُعطي —
هي سلسلة من التغريدات متجددة لأهم التعارضات الدوائية مهمة لصيادلة وللأطباء وأيضًا لكل مهتم بالتثقيف الصحي.
🚫 Sildenafil and Isosorbide Mononitrate
Sildenafil may markedly increase the hypotensive effects of isosorbide mononitrate.
More than 123 deaths have been reported since 1998.
Sildenafil may markedly increase the hypotensive effects of isosorbide mononitrate.
More than 123 deaths have been reported since 1998.
🚫 Potassium Chloride and Spironolactone
The combination may result in hyperkalemia.
The resulting hyperkalemia can be serious and may lead to cardiac failure and death.
The combination may result in hyperkalemia.
The resulting hyperkalemia can be serious and may lead to cardiac failure and death.
🚫 Clonidine and Propranolol
The combination may produce a mysterious hypertension that is unrelated to the pharmacology of either agent when administered independently.
The combination may produce a mysterious hypertension that is unrelated to the pharmacology of either agent when administered independently.
🚫 Warfarin and Diflunisal
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as diflunisal, have been shown to increase the risk for gastrointestinal (GI) bleeding and the anticoagulant response of warfarin.
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as diflunisal, have been shown to increase the risk for gastrointestinal (GI) bleeding and the anticoagulant response of warfarin.
🚫 Bromocriptine and Pseudoephedrine
The interaction can lead to severe peripheral vasoconstriction, ventricular tachycardia, seizures, and possibly death.
The interaction can lead to severe peripheral vasoconstriction, ventricular tachycardia, seizures, and possibly death.
🚫 Ibuprofen and celecoxib
Nonsteroidal anti-inflammatory agents may enhance the toxic effect of other nonsteroidal anti-inflammatory agents.
Specifically, the risk for gastrointestinal toxicity is increased.
Nonsteroidal anti-inflammatory agents may enhance the toxic effect of other nonsteroidal anti-inflammatory agents.
Specifically, the risk for gastrointestinal toxicity is increased.
🚫 Doxazosin and Tamsulosin
Alpha1-Blockers may enhance the antihypertensive effect of other Alpha1-Blockers.
Avoid concomitant use of alpha1 blockers.
Additive pharmacologic effects (hypotension, syncope) might be anticipated.
Alpha1-Blockers may enhance the antihypertensive effect of other Alpha1-Blockers.
Avoid concomitant use of alpha1 blockers.
Additive pharmacologic effects (hypotension, syncope) might be anticipated.
🚫 Clopidogrel and PPI
Esomeprazole and Omeprazole may diminish the antiplatelet effect of Clopidogrel and may decrease serum concentrations of the active metabolite of Clopidogrel.
Pantoprazole may be lower-risk alternative to Esomeprazole and Omeprazole.
Esomeprazole and Omeprazole may diminish the antiplatelet effect of Clopidogrel and may decrease serum concentrations of the active metabolite of Clopidogrel.
Pantoprazole may be lower-risk alternative to Esomeprazole and Omeprazole.
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