Sterile Compounding Preparation
Sterile Compounding Preparation

@SCPreparation

9 تغريدة 57 قراءة Oct 13, 2020
اهلا وسهلا من جديد ...
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🛑!!??Can we use Vancomycin orally
#SCPreparation
Yes, vancomycin can be use orally in case of*Clostridium difficile diarrhea*
🦠What is the dose ?
👨🏻 Adult: 125 mg orally every 6 hours daily for 10 days
👦🏼Pediatric: Clostridium Difficile Infection: 40 mg/kg/day orally divided every 6 to 8 hours for 7 to 10 days.
🛑How?🤷‍♂️ We didn’t have oral dosage form?
By Extemporaneous preparation
Which is prepared by a pharmacist because this dosage form of the drug is not readily available.
نتجه الان للجانب العملي ...
الادوات المطلوبه للتحضير...
Graduated cylinder🧪
Syringe/Needle 💉
Bottle 💊
المحاليل المطلوبه للتحضير...
Sterile water for injection
Water for irrigation
Ora-Sweet
Patient 👨🏻 Ahmed is 30 years old , Diagnosed by Clostridium Difficile Infection🦠, the doctor 👨‍⚕️ order vancomycin125mg Q6H for 10 days...
The Patient need Vancomycin 125mg Q6H for 10 days ..
It’s mean the patient need 5g for 10 days..
We will use 5 vials from Vacomycin 1g...
The concentration should be25mg/ml
It’s mean the total volume will be 200ml
✨The First step...
We will reconstitute every vial by 10ml Sterile water for injection. It’s mean the 5g will be in 50 ml SWFI
✨The Second step...
We will transfer the solution to the graduated cylinder..
✨The Third step...
We will add 75ml water for irrigation and 75ml from Ora-sweet, The total volume will be 200ml in the Graduated cylinder...
✨The last step..
We will transfer the contents from graduated cylinder to the bottle..
Dose = 125mg=5ml Q6H
Stability :
75 days in Refrigerator
26 days in Room temperature

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